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The findings, published in the U.S. journal Science Translational Medicine, suggested that it may be possible to develop a cure for Ebola even after the virus can be detected in the blood and disease symptoms have become apparent.
Although rare Cheap Darius Leonard Jersey , Ebola virus is considered one of the most if not the most aggressive virus known to date in part because of its rapidity to kill, which can be within one week from exposure or three to four days from when the first symptoms become apparent. This leaves very little time for any treatment to act and save a sick individual.
"For this reason, such a treatment has been considered by many to be closer to the domain of science fiction than contemporary scientific research Cheap Quenton Nelson Jersey ," lead author Qiu Xiangguo at the Public Health Agency of Canada told Xinhua.
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The combination of antibody and interferon therapy was 75 percent and 100 percent protective in cynomolgus and rhesus monkeys when given three days post-infection. About half of the cynomolgus monkeys were protected at four days post-infection in cases where only interferon alpha was given earlier, one day post- infection, Qiu said.
"Although we were very optimistic we were not expecting to see 100 percent survival in Ebola-infected non-human primates when treated only three days before they succumb to the disease on average Cheap Khari Willis Jersey ," Qiu said.
"This study shows that what seemed impossible to many, i.e. to develop a cure capable of stopping Ebola virus on its track only a few days before death, has now been made and proven efficacious in conditions that are at least as serious if not more severe than what has been observed and described in humans Cheap Bobby Okereke Jersey ," she added.
The researchers said they have tentatively scheduled a phase I safety trial, slated for the end of 2014 or early 2015, to test the combination therapy in humans.
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